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Studies Show CBD Can Reverse Liver Scarring in Cirrhosis

Emily Robertson
Woman Holding Healthy Liver Pillow

CBD kills the hepatic stellate cells that cause pain and liver scarring.

You may not think of it often, but your liver is your best friend. It is one of the most important organs in the body, and also the largest. Abuse of alcohol or drugs considerably contributes to its decline. Lifestyle damage can be incredibly difficult to repair if liver disease strikes, as this organ will have reduced capacity to heal itself. In the worst cases, damage becomes irreparable. This can result in liver pain, and ultimately, in death.

Or does it?

Recent studies have shown that cannabis may be a leading factor in maintaining and improving hepatic functioning. But what does this mean? And how does it work?

The liver is an absolutely incredible organ. It is crucial to the well being and health of the body. This is due to its detoxing effect on the body. Forget apple diets and green smoothies – the liver works hard every minute to clean your blood and take away toxins. Meanwhile, it helps to process, deliver, and store glucose reserves in order to keep you alive in times of famine and fast in times of danger.

Liver Pain?

When healthy, or even slightly damaged, a liver regenerates the cells required to keep it whole and functioning properly. However, damage can reach a point where it is no longer naturally repairable.

Scarring and liver pain begins at this point in what is called fibrosis and ends in cirrhosis. These are the consequences of long-term, repeated abuse (drugs or alcohol) or disease.

Once cirrhosis starts, it will no longer generate healthy cells. This results in a slow death of the organ, and of the body itself. At that point, symptoms include skin yellowing, fatigue, loss of appetite, itchiness, and weakness.

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How Does Cannabis help Liver Pain and Scarring?

Scientists are only now beginning to understand the mechanisms through which cannabis helps the liver. Researchers believe that liver disease, like many inflammatory conditions, are partially due to an endocannabinoid deficiency.

Any living creature with a vertebrae has what’s called an endocannabinoid system (ECS). This system has a massive network of chemical compounds called endocannabinoids taht engage with receptors called CB1 and CB2. These intersperse throughout the brain, organs, central nervous system, and body to balance metabolic processes and the immune system.

Cannabidiol (CBD), found in cannabis, according to two studies in 2011 have found, helps to treat liver disease by killing hepatic stellate cells (HSC) that cause scar tissue. Ultimately, CBD helps to restore regular functioning of the liver, as well as neurological functioning that HSC damages.

In Conclusion:

Most of these studies have progressed to the animal testing phase.  CBD treatment for disease has been successful in rats and mice. This means that it has a high potential to restore healthy cells in humans and potentially reverse the damages of liver disease.

Do you know anyone suffering from liver disease who could benefit from this study? Share and let them find out if cannabis can help them.

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RxLeaf Patient Story: Jill, Liver Disease

Jill is an RxLeaf Patient who uses cannabis to medicate following liver disease and a transplant. Jill’s liver pain is less of an issue when she’s properly medicated. Below is a segment of her story, more of which can be read by clicking here.

“I spent the rest of my 20s heavily medicated and not living a fulfilled life I was used to. Also my sub-conscious was programmed that I would need a transplant one day which was mentally exhausting. I have been on countless kinds of medications over the last 12 years to manage mood, sleep, pain, nausea and depression. Sometimes the medications did what they were supposed to, but the side effects were almost always as bad as the initial problem. Constantly dealing with stomach aches, head aches, vomiting, weight gain, poor sleep and an unstable mood that distinguished my healthy life style.”

“I came to try medical cannabis to manage symptoms when my liver was incapable of processing pain medications, as they were not good for a failing liver. At first I used an Indica strain that had 7-10% THC / 8-11% CBD. This helped with mood, nausea, sleep, appetite, and pain. After troubleshooting, I have found great results since I have been using medical cannabis oil with 65% CBD / 12%THC which this treatment has greatly improved my mood and my sleep. I take cannabis oil about two times a week and smoke cannabis maybe 5 times a week.”

Emily Robertson

Emily Robertson has been writing freelance and contract work since 2011. She has written on a variety of topics, including travel writing of North America and the growing legalized cannabis industry across the globe. Robertson has a master’s degree in literature and gender studies, and brings this through in her writing by always trying to explore different perspectives. Born and raised in southwestern Ontario, Robertson moved to Glasgow, Scotland in 2016 to undergo her doctorate in Scottish Literature. She lives in the West End with her dog, Henley.

6 Comments
  • Avatar
    Richard Gilbert

    I am a person who uses CBD oil for that reason. Just stopped drinking alcohol about 6 months ago after my doctor said l had beginning cirrossis. I have decided to be a human test subject for this. Now l just wish l could get some free CBD oil. Lol, anyone interested in this matter l would be happy to try your product.

    March 10, 2018 at 3:12 pm Reply
    • Avatar
      RxLeaf

      Congrats on getting sober, Richard! Amazing feat.

      March 11, 2018 at 2:20 am Reply
  • Avatar
    Richard Gilbert

    Using 500 mg medterra hemp oil currently, have been trying it about 2 weeks so l will keep you posted on the progress.

    March 10, 2018 at 3:17 pm Reply
    • Avatar
      sonja rose

      Hi Richard, im interested in your progress, would love to hear if the good oil has helped 🙂

      July 1, 2019 at 2:52 am Reply
  • Avatar
    sonja rose

    What Dosage would one take and what ratio of cbd and thc? I have searched and searched and can find nothing.

    July 1, 2019 at 2:48 am Reply
    • Avatar
      Mirk

      It’s still largely unresearched. People get to be their own guinea pigs. At least, you could be testing worse substances 😉

      I’d start with a 10:1 in favour of CBD myself. A little bit of THC helps activate CBD receptors throughout the body, I’ve heard. If you want to guage effect you should do a month with CBD only, then 10:1 CBD/THC, then 5:1, 1:1. You can even take it further if you value science more than health 😉 Go back up the scale, but take stronger concentrations of THC rather than CBD. I’d just stop at the 1:1, personally.

      November 11, 2019 at 12:55 am Reply

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